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| General Secretary |
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| Dr. Prem Man Singh Chauhan,FRSC |
| Medicinal Chemistry Division,
Central Drug Research Institute |
| Lucknow -226001, India |
| Email: premsc58@hotmail.com,
prem_chauhan_2000
@yahoo.com |
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| Post Doctoral
Experience |
Jan 1987
- Oct 1988 |
| Senior Research Associate (Engineering
and Physical Sciences Research Council (EPSRC), U.K.)
Robert Robinson Laboratory, University of Liverpool, UK
( with Dr.R.C.Storr) |
| DAAD Visiting
Scientist |
April 2000
- July 2000 |
| Senior DAAD Visiting Scientist,
Instituted of Organic Chemistry, Aachen, Germany (with
Prof.D.Enders and Prof Stefan Brease) |
| Post Doctoral
Senior Research Associate |
2002 - 2003 |
| School of Chemical Sciences,
University East Anglia, Norwich, UK ( with Prof.David
Horwell) |
| Research Experience |
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| Synthetic Organic Chemistry
(23 years), Medicinal Chemistry (23 years), Combinatorial
Chemistry (6years) |
| Current area of Interest |
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| Combinatorial chemistry of
biologically active heterocycles |
| Total Paper : 50 |
| Patents : 7 |
| Selected
Publications |
- Perspective in Antimalarial Chemothrapy, Arun Kumar,
Sanjai B. Katiyar, Anu agarwal , P.M.S. Chauhan*,
Current Medicinal Chemistry, 2003,10,1137-50.
- Current Trends in Antimalarial Chemotherapy, Arun
Kumar, Sanjai ,B. Katiyar, Anu agarwal , P.M.S.
Chauhan*, Drugs of the Future, 2003 Vol. 28, No.
3 ,243-255 YEAR 2002.
- Syntheses of novel Antimycobacterial Combinatorial
libraries of structurally diverse substituted pyrimidines
by three component solid phase reactions ,Arun Kumar,
Sudhir Sinha and PMS Chauhan* , Bioorganic and Medicinal
Chemistry Letters ,2002, 12, 667-669.
- Solid phase synthesis of Structurally diverse
tetra substituted pyrimidines for potential use in
combinatorial chemistry ,PMS Chauhan* and Arun Kumar
, Combinatorial Chemistry and High Throughput Screening,
2002, 5, 93-95.
- Recent development of combinatorial syntheses
of Biological active Nitrogen heterocycles, Sanjy
K. Shrivastava , P.M.S. Chauhan* Combinatorial
Chemistry and High Throughput Screening, 2001,4, 35-51.
- Present trends and future strategy in Chemotherapy
of Malaria, Sanjy K. Shrivastava , P.M.S. Chauhan*,
Current Medicinal Chemistry, 2001,8,1535-42.
- Quinolones : Novel Probes in Antifilarial Chemotherapy.
S. Srivastava, P. M. S. Chauhan*, A. P. Bhaduri ,
N Fatima, R. K. Chatterjee, J .Medicinal Chemistry,
2000 43,2275-79.
- Synthesis and Antifilarial profile of 7-Chloro
4- substituted amino quinolines : A new antifilarial
agents. S. Tiwari , P.M.S. Chauhan*, A.P. Bhaduri
, S.N. Singh , Nigar Fatima , R.K. Chatterjee, Bioorganic
and Medicinal Chemistry Letters ,2000,10,1409-12.
- Secondary amines as new pharmacophores as for macrofilaricidal
drug. S. Srivastava, P. M. S. Chauhan*, A. P. Bhaduri
, N Fatima, R. K. Chatterjee, Bioorganic and Medicinal
Chemistry Letters, 2000, 10, 313-314.
- Currents and Potential Filariacides , P.M.S.
Chauhan*, Drugs of the Future , 2000,25,481-488
- PS-15 , P.M.S. Chauhan*, Current Opinion
in infective investigational Drugs,2000, 2,103.
- Potent 1,3- disubstitued 9H-pyrido [3,4-b] indoles
as new lead compounds in antifiarial chemotherapy
, Sanjay K. Shrivastava, A. Agarwal , P.M.S. Chauhan*,
S.K. Agarwal , A.P. Bhaduri , S.N. Singh , Nigar Fatima
, R.K. Chatterjee , J. Medicinal Chemistry (1999)
, 42, 1667-1672.
- Solid support syntheses of Quinolones , S. Srivastava
, W. Haq., P.K. Murthy , & P.M.S. Chauhan*
, Bioorganic and Medicinal Chemistry Letters , (1999)
, 9 , 1885-1888.
- Sanjay K. Shrivastava, A. Agarwal , P.M.S. Chauhan*,
S.K. Agarwal , A.P. Bhaduri , S.N. Singh , Nigar Fatima
, R.K. Chatterjee , , Bioorganic and Medicinal Chemistry
(1999) 7(6), 1223-236.
- Novel strategy for N-alkylation of primary amines
Sanjy K. Shrivastava , P.M.S. Chauhan*, A.P.
Bhaduri , Synth. Comm. (1999) , 29(12), 2085.
- Solid Phase Syntheses of structurally diverse pyrimido
[4 ,5-d] pyrimidines for potential use in combinatorial
chemistry. S. Srivastava , W. Haq. & P.M.S. Chauhan*,
Bioorganic and Medicinal Chemistry Letters ,(1999)
, 9 , 965-66.
- Novel solid support approach to substituted pyrimidines
and their conversion in to condensed heterocycles
for the potential use in the combinatorial chemistry.
S. Srivastava W. Haq, P.M.S. Chauhan*, Combinatorial
Chemistry and High Through put Screening (1999) ,
p33-38.
- Syntheses of 7 -chloro-4 -substituted amino quinolines
and their ability to produce methemoglobin in canine
hemolysate S. Shrivastava , S. Tiwari , Sanjy K. Shrivastava
, P.M.S. Chauhan, A.P. Bhaduri , V.C. Pandey , Bioorganic
and Medicinal Chemistry Letters ,(1997) , Vol. 7 ,
2741-2746.
- Correlation between inhibition of growth and arginine
transport of leishmania donovani promastigotes in
vitro by Diamidines. Mamta Kandpal , Babu L. Tekwani
, P.M.S. Chauhan, A.P. Bhaduri , Life Sciences (1996)
, 59 , No. 7 , 75-80
- Novel site specific one step bromination of substituted
benzenes, Sanjy K. Shrivastava , P.M.S. Chauhan*,
A.P. Bhaduri , J. Chem. Soc. Chem. Comm. (1996) ,
2679-2680.
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